Diabetes mellitus is a
syndrome of metabolic disease characterized by high levels
of sugar (glucose) in the blood. It is caused by a deficiency
of insulin secretion from your pancreas or insulin action,
or both. This causes the abnormal metabolism of carbohydrates,
protien and fat. It is the most common endocrine-metabolic
disorder of childhood and adolescence.
Individuals affected by Type 1 Diabetes
confront serious burdens that include:
Absolute daily requirement for exogenous
insulin
Need to monitor their own metabolic control
Need to pay constant attention to dietary control
Normal
and target blood glucose ranges (mg/dL) |
Normal
blood glucose levels in people who do not have
diabetes |
Upon
waking (fasting) |
70 to
110 |
After meals |
70 to 140 |
Target
blood glucose levels in people who have diabetes |
Before meals |
90 to 130 |
1 to 2 hours after
the start of a meal |
less than 180 |
Hypoglycemia (low
blood glucose) |
70 or below |
Symptoms of Diabetes
The symptoms of Diabetes may include:
- Frequent thirst (Polydypsia)
- Frequent hunger (Polyphagia)
- Frequent urination (Polyuria)
- Unusual weight loss
- Irritibility
- Increased fatigue
- Blurry vision
- Wounds that do not heal normally
If you have one or more of these diabetes symptoms, see your
doctor right away.
Type 1 Diabetes
Type 1 diabetes is usually diagnosed in
children and young adults. It is characterized by a severe
deficiency of insulin and is dependent on an additional
source of insulin to prevent ketosis and perserve life.
It was formally known as insulin-dependent diabetes mellitus
or juvenile-onset diabetes mellitus. It is caused by a
deficiency of insulin or inaction of insulin or both. Insulin
is important and necessary to allow sugar to be used as
fuel in your body's cells. Without it, sugar is metabolized
inefficiently. Finding out you have diabetes is serious,
and Type 1 is the most serious, but you can live a long,
healthy life with Type 1.
Some of the conditions associated with
Type 1 Diabetes include high blood sugar (hyperglycemia),
low blood sugar (hypoglycemia), ketoacidosis, and celiac
disease. Complications of Type 1 include heart disease
(cardiovascular), blindness, nerve damage or kidney damage.
If you have Type 1 Diabetes, the time
you spend on preventive care like eye care, foot care and
skin care, as well as your heart health and oral care could
delay or prevent the onset of dangerous complications later
in life.
Type 2 Diabetes
Type 2 diabetes is the most common form
of diabetes. This was formally called adult-onset diabetes
mellitus or non-insulin dependent diabetes. Persons in
this type of diabetes are not insulin dependent and only
infrequently develop ketosis. In Type 2 Diabetes, either
the body does not produce enough insulin or the cells ignore
the insulin.
When glucose builds up in the blood (hyperglycemia)
because of a lack of insulin, and does not go into your
cells, it can cause two problems:
- Immediately, your cells may be starved for energy
- Over time, your eyes, kidneys, nerves, or heart
may be hurt due to the high blood glucose level
Type 2 Diabetes is serious, but you can
live a long, healthy life with proper care. While Diabetes
can occur in people of all ages and races, Type 2 Diabetes
is more common in African Americans, Latinos, Native Americans,
Asian Americans, and Pacific Islanders.
Gestational Diabetes
Pregnant women who have never had diabetes before but
who have high blood sugar (glucose) levels during pregnancy
are said to have gestational diabetes. About 4% of all
pregnant women (135,000 cases) are affected with gestational
diabetes each year. They are identified by a 2-hour Glucose
Tolerance Test.
The exact cause of gestational diabetes is not known,
but there are some clues to the cause. Your placenta supports
your baby as it grows. Hormones from the placenta help
your baby develop. These same hormones appear to block
the action of your insulin in your body. This is called
insulin resistance and it makes it hard for your body to
use insulin. You may need up to three (3) times as much
insulin as when you are not pregnant.
Gestational diabetes affects you late in the pregnancy
after your baby's body is formed, but still growing. The
kinds of birth defects seen are different than in those
babies whose mothers have had diabetes before they became
pregnant. Untreated or poorly controlled gestational diabetes
can hurt your baby. When you have gestational diabetes,
your insulin does not control your blood sugars and your
pancreas is producing more insulin. The insulin you produce
does not cross the placenta, so your baby gets a high blood
sugar too. Your baby's pancreas produces extra insulin
to lower it's blood sugar and helps convert the sugar to
fat. When your deliver your baby, the "candy store" is
closed and the extra source of sugar is stopped. Immediately
after birth, your baby can get hypoglycemic and have respiratory
problems. Also, since the sugar was converted to fat, your
baby may have "macrosomia" or look like a "fat
baby." This puts your baby at risk for congenital
(at birth) heart problems. Babies with excess insulin become
children who are at risk for developing Type 2 Diabetes.
Often diabetes goes undiagnosed because many of its symptoms
seem so harmless or present slowly. Recent studies indicate
that the early detection of diabetes symptoms and treatment
can decrease the chance of developing the complications
of diabetes. Family history is also important in assessing
your risk of developing diabetes.
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